Arizona Cardinals: Week 5 Recap & Week 6 Forecast

Week 5 · 2025 · October 10, 2025

Tennessee Titans
21

Arizona Cardinals
22

Epic collapse: blew 21-3 lead. Third straight loss by walk-off FG (NFL first). Emari Demercado fumbled before goal line (touchback). DB fumbled INT return (Titans TD). Mentally destroyed.

Analytics

  • Blew 21-3 lead in epic collapse
  • Third straight loss by walk-off FG (NFL FIRST in history)
  • Emari Demercado fumble before goal line (touchback)
  • DB fumbled INT return (led to Titans TD)
  • Team is mentally destroyed and broken
  • 2-0 ATS on road but 2-3 overall

Injuries

Injuries: QB Kyler Murray (foot) briefly left, said "we'll see". LB Cody Simon OUT. TE Tip Reiman carted off.

Betting Intel

Week 6: Cardinals +5.5 at Colts. Total: 47.5 O/U. Cardinals 2-0 ATS on road but mentally broken.

Fantasy Deep Dive

Fantasy: Kyler Murray QB1 when healthy (monitor foot). Marvin Harrison Jr. inconsistent but WR1 upside. James Conner RB2.

Week 5 Forecast:

Forecast: See Colts writeup. Cardinals destroyed mentally.

BEST BET: Colts -5.5